Tag: ageing

The Epigenetic Clock and Longevity

Category: Healthcare Advances Written by Dr. Charles Shively / February 10, 2017

Many alterations occur to our genome or DNA as we age. Some of these changes are epigenetic modifications to our DNA without altering the genetic sequence itself. The human genome is the complete assembly of DNA (deoxyribonucleic acid) that makes each individual unique. The genome consists of about 3 billion base pairs...half from the mother and half from the father. DNA holds the instructions for building the proteins that carry out a variety of functions in a cell. Chemical compounds and proteins that can attach to DNA comprise what is known as the epigenome. These epigenomic compounds attach to DNA as "tags" and change the way individual cells use the DNA's instructions. Importantly these tags or "marks"... as they are known... do not change the sequence of the DNA but rather how the cells operate. Read more ...

Considerations at The Intersection of Cognitive Ageing and Psychobiology

Category: Healthcare Advances Written by Dr. Charles Shively / February 8, 2017

Cognitive decline is a normal consequence of the age-related changes in the physiology of the brain and the larger senescence every human being experiences. Cognitive decline is often presumed, by the unknowing, to be a precursor to dementia. It is not. Dementia is not a part of normal aging. It represents a group of symptoms caused by disorders that affect the ability to think so severely that it impairs one's ability to perform normal activities like eating or getting dressed. Memory loss is a common symptom of dementia, but memory loss by itself does not mean that someone has dementia. Age-related memory loss as part of cognitive decline manifests itself as the rare occasion, for example, of making a bad decision, missing a monthly payment, forgetting which day it is and remembering later, sometimes forgetting which word to use or losing things from time to time. Read more ...

Nutritional Influence on Cognitive Decline

Category: Healthcare Advances Written by Dr. Charles Shively / February 8, 2017

The First Stage of Cognitive Decline Cognitive decline is associated with various neurodegenerative diseases which are caused by changes in the brain possessing neurotransmission decay. These neurodegenerative diseases can include mild cognitive impairment (MCI), Memory Loss, Alzheimer’s disease, other Dementias and in certain cases Parkinson’s Disease. Read more ...

Senescence and Nutrition

Category: Healthcare Advances Written by Dr. Charles Shively / January 13, 2017

Dehabilitation or Regeneration? If one visits various dictionaries, the definition of senescence typically includes reference to the process of aging and the degenerative loss of various body functions or processes. In brief,”one who begins to age”. Age-related loss of function is a trait of virtually all organisms that age. In humans, age-related degeneration gives rise to a host of well-recognized challenges: atherosclerosis and heart failure, osteoporosis, macular degeneration, pulmonary insufficiency, renal failure, neurodegeneration (for example Alzheimer’s and Parkinson’s diseases) and various others. These changes begin to show them typically mid-life beginning in the 50-60 years of age range. From a pathological standpoint it is typically about debilitating losses of tissue or cellular function.  Read more ...

Feminine Forever Articles

Category: Healthcare Advances Written by Multiple Authors / November 8, 2014

Feminine Forever Articles (Hosted on DropBox) Feminine Forever Articles

Articles of Interest

Category: Healthcare Advances Written by Multiple Authors / November 7, 2014

Please visit this DropBox with a list of interesting articles:  Articles of Interest

Reelin’ In Quality of Life: Are You Ridin’ On?

Category: Healthcare Advances Written by Dr. Charles Shively / November 6, 2014

How is it we have Quality of LIfe? Female or male…who here wants to get their Quality of Life back? Are you a Searcher? Ready for Advancement and SLOWING AGE PROCESSES?  I’m in. Are You? Read more ...

Pharmacist to Pharmacist Healthcare: “I Have Alzheimer’s”

Category: Healthcare Advances Written by Dr. Charles Shively / July 24, 2014

Unexpected Pharmacy Workflow Challenge...Sound Familiar? This past week during a visit to perform one of my consultant complimentary independent pharmacy workflow assessments, the pharmacist/ owner offered...almost immediately before we started the assessment..."I have Alzheimer's". Momentarily taken back, I then asked: "Why do you believe this?" The individual said: "My memory is failing. I go to do one thing and get distracted by something else and wind up doing something different. I only remember what I went to do when I come back to where I first had the thought". Sound familiar? Read more ...